Syphilis Laboratory Guidelines: Performance Characteristics of Nontreponemal Antibody Tests
نویسندگان
چکیده
منابع مشابه
Canadian Public Health Laboratory Network laboratory guidelines for the use of direct tests to detect syphilis in Canada
Treponema pallidum subsp. pallidum and/or its nucleic acid can be detected by various methods such as microscopy, rabbit infectivity test or polymerase chain reaction (PCR) tests. The rabbit infectivity test for T. pallidum, although very sensitive, has been discontinued from most laboratories due to ethical issues related to the need for animal inoculation with live T. pallidum, the technicall...
متن کاملA female with positive serum nontreponemal tests
| April 2015 | 422 antibodies that cause reactivity in a nontreponemal test with the positive treponemal test result, termed a biologic false positive (BFP) reaction.[3] Many infections and diseases particularly systemic lupus erythematosus are more likely to cause BFP. CSF examination should be performed in all persons with serologic evidence of syphilis infection and neurologic symptoms.[6] T...
متن کاملCanadian Public Health Laboratory Network laboratory guidelines for the use of serological tests (excluding point-of-care tests) for the diagnosis of syphilis in Canada
Syphilis, caused by the bacterium Treponema pallidum subsp. pallidum, is an infection recognized since antiquity. It was first reported at the end of the 15th century in Europe. Infections may be sexually transmitted as well as spread from an infected mother to her fetus or through blood transfusions. The laboratory diagnosis of syphilis infection is complex. Because this organism cannot be cul...
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Introduction This paper is part of a series on immunologic testing guidelines. The series introduction (1) outlines the full methodology for obtaining data, grading the literature, combining the information from multiple sources, and developing recommendations. Briefly, MEDLINE and Healthstar were searched using a variety of search terms, and all relevant available literature was reviewed. All ...
متن کاملBlood spot screening and confirmatory tests for syphilis antibody.
We developed a blood spot test for syphilis antibody using enzyme-linked immunosorbent assay (ELISA) technology. Dried blood was eluted by buffered saline or, for a supplementary confirmatory test, by treponemal-antibody test diluent. Eluates were diluted in an absorption buffer (Calypte Biomedical, Berkeley, Calif.) and added to plate wells coated with cardiolipin antigen (ADI Diagnostics, Tor...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2020
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/ciaa306